4C2S

Crystal structure of the fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA P156L mutant) in complex with UDP and deoxy-H-antigen acceptor

4C2S の概要

• エントリーDOI: 10.2210/pdb4c2s/pdb
• 分子名称: HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, alpha-L-fucopyranose-(1-2)-hexyl 3-deoxy-beta-D-galactopyranoside, MANGANESE (II) ION, ... (5 entities in total)
• 機能のキーワード: gta, abo, blood group antigen, glycosylation, transferase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69833.85

構造登録者

Weadge, J.T.,Palcic, M.,Henriksen, A. (登録日: 2013-08-19, 公開日: 2013-09-11, 最終更新日: 2023-12-20)

• 主引用文献: Weadge, J.T.,Palcic, M.,Henriksen, A.; Structural and Biochemical Characterization of the Human Blood Group a and B Galactosyltransferases Posessing the Pro156Leu Mutation; To be Published,

実験手法

X-RAY DIFFRACTION (2.48 Å)