4C1C
Crystal structure of the metallo-beta-lactamase BCII with D-captopril
Summary for 4C1C
Entry DOI | 10.2210/pdb4c1c/pdb |
Related | 4BZ3 4C09 4C1D 4C1E 4C1F 4C1G 4C1H |
Descriptor | BETA-LACTAMASE 2, GLYCEROL, SULFATE ION, ... (6 entities in total) |
Functional Keywords | hydrolase, mbl. metallo-beta-lactamase, antibiotic resistance |
Biological source | BACILLUS CEREUS |
Cellular location | Periplasm : P04190 |
Total number of polymer chains | 1 |
Total formula weight | 25623.89 |
Authors | Zollman, D.,Brem, J.,McDonough, M.A.,van Berkel, S.S.,Schofield, C.J. (deposition date: 2013-08-12, release date: 2014-08-27, Last modification date: 2023-12-20) |
Primary citation | Brem, J.,van Berkel, S.S.,Zollman, D.,Lee, S.Y.,Gileadi, O.,McHugh, P.J.,Walsh, T.R.,McDonough, M.A.,Schofield, C.J. Structural Basis of Metallo-beta-Lactamase Inhibition by Captopril Stereoisomers. Antimicrob. Agents Chemother., 60:142-150, 2015 Cited by PubMed: 26482303DOI: 10.1128/AAC.01335-15 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.18 Å) |
Structure validation
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