Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008270 | molecular_function | zinc ion binding |
A | 0008800 | molecular_function | beta-lactamase activity |
A | 0016787 | molecular_function | hydrolase activity |
A | 0017001 | biological_process | antibiotic catabolic process |
A | 0042597 | cellular_component | periplasmic space |
A | 0046677 | biological_process | response to antibiotic |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 1258 |
Chain | Residue |
A | LYS95 |
A | GLU130 |
A | ARG131 |
A | HOH2065 |
A | HOH2267 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 1259 |
Chain | Residue |
A | HOH2094 |
A | HOH2177 |
A | HOH2210 |
A | HOH2268 |
A | ALA117 |
A | ASN148 |
A | THR180 |
A | ASP182 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 1260 |
Chain | Residue |
A | LYS103 |
A | LYS169 |
A | GLN190 |
A | HOH2183 |
site_id | AC4 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE MCO A 1261 |
Chain | Residue |
A | HIS118 |
A | ASP120 |
A | HIS179 |
A | LYS201 |
A | LEU208 |
A | GLY209 |
A | ASN210 |
A | HIS240 |
A | ZN1262 |
A | ZN1263 |
A | HOH2091 |
A | HOH2173 |
A | HOH2188 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN A 1262 |
Chain | Residue |
A | ASP120 |
A | CYS198 |
A | HIS240 |
A | MCO1261 |
A | HOH2091 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN A 1263 |
Chain | Residue |
A | HIS116 |
A | HIS118 |
A | HIS179 |
A | MCO1261 |
A | HOH2091 |
Functional Information from PROSITE/UniProt
site_id | PS00743 |
Number of Residues | 20 |
Details | BETA_LACTAMASE_B_1 Beta-lactamases class B signature 1. IiTHaHADriGGiktlker.G |
Chain | Residue | Details |
A | ILE113-GLY132 | |
site_id | PS00744 |
Number of Residues | 13 |
Details | BETA_LACTAMASE_B_2 Beta-lactamases class B signature 2. PqynILvGgCLVK |
Chain | Residue | Details |
A | PRO189-LYS201 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS116 | |
A | HIS118 | |
A | HIS179 | |
Chain | Residue | Details |
A | ASP120 | |
A | CYS198 | |
A | HIS240 | |
Chain | Residue | Details |
A | LYS201 | |
Chain | Residue | Details |
A | ASN210 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 16 |
Chain | Residue | Details |
A | HIS116 | metal ligand |
A | HIS118 | metal ligand |
A | ASP120 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | HIS179 | metal ligand |
A | ASN210 | electrostatic stabiliser, hydrogen bond donor |