4C09

Crystal structure of the metallo-beta-lactamase BCII

Summary for 4C09

• Entry DOI: 10.2210/pdb4c09/pdb
• Related: 4BZ3 4C1C 4C1D 4C1E 4C1F 4C1G 4C1H
• Descriptor: BETA-LACTAMASE 2, GLYCEROL, SULFATE ION, ... (5 entities in total)
• Functional Keywords: hydrolase, mbl, metallo-beta-lactamase, antibiotic resistance
• Biological source: BACILLUS CEREUS
• Cellular location: Periplasm : P04190
• Total number of polymer chains: 1
• Total formula weight: 25407.59

Authors

Zollman, D.,Brem, J.,McDonough, M.A.,van Berkel, S.S.,Schofield, C.J. (deposition date: 2013-07-31, release date: 2014-08-20, Last modification date: 2023-12-20)

• Primary citation: Brem, J.,van Berkel, S.S.,Zollman, D.,Lee, S.Y.,Gileadi, O.,McHugh, P.J.,Walsh, T.R.,McDonough, M.A.,Schofield, C.J.; Structural Basis of Metallo-beta-Lactamase Inhibition by Captopril Stereoisomers.; Antimicrob. Agents Chemother., 60:142-150, 2015; PubMed: 26482303; DOI: 10.1128/AAC.01335-15

Experimental method

X-RAY DIFFRACTION (1.2 Å)