4BW5
Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1)
Summary for 4BW5
Entry DOI | 10.2210/pdb4bw5/pdb |
Descriptor | POTASSIUM CHANNEL SUBFAMILY K MEMBER 10, POTASSIUM ION, CADMIUM ION, ... (4 entities in total) |
Functional Keywords | transport protein, outward rectification, membrane protein, k2p |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 4 |
Total formula weight | 126358.34 |
Authors | Pike, A.C.W.,Dong, Y.Y.,Dong, L.,Quigley, A.,Shrestha, L.,Mukhopadhyay, S.,Strain-Damerell, C.,Goubin, S.,Grieben, M.,Shintre, C.A.,Mackenzie, A.,Vollmar, M.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Burgess-Brown, N.,Carpenter, E.P. (deposition date: 2013-06-30, release date: 2013-07-31, Last modification date: 2023-12-20) |
Primary citation | Pike, A.C.W.,Mackenzie, A.,Mcclenaghan, C.,Aryal, P.,Dong, L.,Quigley, A.,Grieben, M.,Goubin, S.,Mukhopadhyay, S.,Ruda, G.F.,Clausen, M.V.,Cao, L.,Brennan, P.E.,Burgess-Brown, N.A.,Sansom, M.S.P.,Tucker, S.J.,Carpenter, E.P. K2P Channel Gating Mechanisms Revealed by Structures of Trek-2 and a Complex with Prozac Science, 347:1256-, 2015 Cited by PubMed: 25766236DOI: 10.1126/SCIENCE.1261512 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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