4BVN

Ultra-thermostable beta1-adrenoceptor with cyanopindolol bound

Summary for 4BVN

• Entry DOI: 10.2210/pdb4bvn/pdb
• Descriptor: BETA-1 ADRENERGIC RECEPTOR, SODIUM ION, 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, ... (6 entities in total)
• Functional Keywords: signaling protein
• Biological source: MELEAGRIS GALLOPAVO (TURKEY)
• Total number of polymer chains: 1
• Total formula weight: 38910.10

Authors

Miller, J.,Nehme, R.,Warne, T.,Edwards, P.C.,Leslie, A.G.W.,Schertler, G.,Tate, C.G. (deposition date: 2013-06-26, release date: 2014-04-02, Last modification date: 2023-12-20)

• Primary citation: Miller-Gallacher, J.L.,Nehme, R.,Warne, T.,Edwards, P.C.,Schertler, G.F.X.,Leslie, A.G.W.,Tate, C.G.; The 2.1 A Resolution Structure of Cyanopindolol-Bound Beta1- Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor.; Plos One, 9:92727-, 2014; PubMed: 24663151; DOI: 10.1371/JOURNAL.PONE.0092727

Experimental method

X-RAY DIFFRACTION (2.1 Å)