4BTF

Structure of MLKL

Summary for 4BTF

Entry DOI	10.2210/pdb4btf/pdb
Descriptor	MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN, FORMIC ACID, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	transferase, pseduokinase, necroptosis
Biological source	MUS MUSCULUS (HOUSE MOUSE)
Total number of polymer chains	1
Total formula weight	54026.95
Authors	Czabotar, P.E.,Murphy, J.M. (deposition date: 2013-06-16, release date: 2013-09-18, Last modification date: 2019-04-24)
Primary citation	Murphy, J.M.,Czabotar, P.E.,Hildebrand, J.M.,Lucet, I.S.,Zhang, J.-G.,Alvarez-Diaz, S.,Lewis, R.,Lalaoui, N.,Metcalf, D.,Webb, A.I.,Young, S.N.,Varghese, L.N.,Tannahill, G.M.,Hatchell, E.C.,Majewski, I.J.,Okamoto, T.,Dobson, R.C.J.,Hilton, D.J.,Babon, J.J.,Nicola, N.A.,Strasser, A.,Silke, J.,Alexander, W.S. The Pseudokinase Mlkl Mediates Necroptosis Via a Molecular Switch Mechanism Immunity, 39:443-, 2013 Cited by PubMed: 24012422 DOI: 10.1016/J.IMMUNI.2013.06.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.604 Å)

Structure validation