4BS6

MOUSE CATHEPSIN S WITH COVALENT LIGAND

Summary for 4BS6

• Entry DOI: 10.2210/pdb4bs6/pdb
• Related: 4BQV 4BS5 4BSQ
• Descriptor: CATHEPSIN S, GLYCEROL, (2S,4R)-4-[2-chloranyl-4-(4-ethylpiperazin-1-yl)phenyl]sulfonyl-N-[1-(iminomethyl)cyclopropyl]-1-[1-(trifluoromethyl)cyclopropyl]carbonyl-pyrrolidine-2-carboxamide, ... (4 entities in total)
• Functional Keywords: hydrolase, cysteine protease, covalent ligand
• Biological source: MUS MUSCULUS (HOUSE MOUSE)
• Cellular location: Lysosome: O70370
• Total number of polymer chains: 2
• Total formula weight: 50625.22

Authors

Banner, D.W.,Benz, J.,Gsell, B.,Stihle, M.,Ruf, A.,Haap, W. (deposition date: 2013-06-07, release date: 2014-06-18, Last modification date: 2024-05-01)

• Primary citation: Haap, W.,Banner, D.W.; Cathepsin S Nitrile Inhibitors; To be Published,

Experimental method

X-RAY DIFFRACTION (1.2 Å)