4BQV

MOUSE CATHEPSIN S WITH COVALENT LIGAND

Summary for 4BQV

• Entry DOI: 10.2210/pdb4bqv/pdb
• Related: 4BPV
• Descriptor: CATHEPSIN S, (2S,4R)-N-(1-cyanocyclopropyl)-1-(1-methylcyclopropanecarbonyl)-4-[4-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)phenyl]sulfonylpyrrolidine-2-carboxamide (3 entities in total)
• Functional Keywords: hydrolase, cysteine protease
• Biological source: MUS MUSCULUS (HOUSE MOUSE)
• Cellular location: Lysosome: O70370
• Total number of polymer chains: 8
• Total formula weight: 201855.98

Authors

Banner, D.W.,Benz, J.,Gsell, B.,Stihle, M.,Ruf, A.,Haap, W. (deposition date: 2013-06-03, release date: 2014-06-18, Last modification date: 2024-11-13)

• Primary citation: Haap, W.,Banner, D.W.; Cathepsin S Nitrile Inhibitors; To be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)