Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008234 | molecular_function | cysteine-type peptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008234 | molecular_function | cysteine-type peptidase activity |
| E | 0006508 | biological_process | proteolysis |
| E | 0008234 | molecular_function | cysteine-type peptidase activity |
| F | 0006508 | biological_process | proteolysis |
| F | 0008234 | molecular_function | cysteine-type peptidase activity |
| G | 0006508 | biological_process | proteolysis |
| G | 0008234 | molecular_function | cysteine-type peptidase activity |
| H | 0006508 | biological_process | proteolysis |
| H | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE 8PW A 1341 |
| Chain | Residue |
| A | GLN141 |
| A | MET194 |
| A | GLY260 |
| A | VAL285 |
| A | ASN286 |
| A | HIS287 |
| A | TYR334 |
| A | HOH2031 |
| A | HOH2084 |
| A | HOH2088 |
| A | HOH2173 |
| A | GLY145 |
| F | ARG130 |
| F | GLU131 |
| A | ALA146 |
| A | CYS147 |
| A | TRP148 |
| A | LYS187 |
| A | GLY191 |
| A | GLY192 |
| A | TYR193 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 8PW B 1341 |
| Chain | Residue |
| B | GLN141 |
| B | GLY145 |
| B | ALA146 |
| B | CYS147 |
| B | TRP148 |
| B | GLY191 |
| B | GLY192 |
| B | TYR193 |
| B | MET194 |
| B | GLY260 |
| B | VAL285 |
| B | ASN286 |
| B | HIS287 |
| B | TYR334 |
| B | HOH2026 |
| B | HOH2050 |
| B | HOH2053 |
| B | HOH2054 |
| B | HOH2113 |
| E | ARG130 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 8PW C 1341 |
| Chain | Residue |
| C | GLN141 |
| C | GLY145 |
| C | ALA146 |
| C | CYS147 |
| C | TRP148 |
| C | GLY191 |
| C | GLY192 |
| C | TYR193 |
| C | MET194 |
| C | GLY260 |
| C | VAL285 |
| C | ASN286 |
| C | HIS287 |
| C | TYR334 |
| C | HOH2023 |
| C | HOH2044 |
| C | HOH2045 |
| C | HOH2107 |
| G | ARG130 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE 8PW D 1341 |
| Chain | Residue |
| D | GLN141 |
| D | GLY145 |
| D | ALA146 |
| D | CYS147 |
| D | TRP148 |
| D | LYS187 |
| D | GLY191 |
| D | GLY192 |
| D | TYR193 |
| D | MET194 |
| D | GLY260 |
| D | VAL285 |
| D | ASN286 |
| D | HIS287 |
| D | TYR334 |
| D | HOH2032 |
| D | HOH2076 |
| D | HOH2079 |
| D | HOH2080 |
| D | HOH2166 |
| H | ARG130 |
| H | GLU131 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 8PW E 1341 |
| Chain | Residue |
| E | HOH2022 |
| E | HOH2043 |
| E | HOH2089 |
| B | LYS272 |
| B | ASN312 |
| C | ARG235 |
| E | GLN141 |
| E | GLY145 |
| E | ALA146 |
| E | CYS147 |
| E | TRP148 |
| E | GLY191 |
| E | GLY192 |
| E | TYR193 |
| E | MET194 |
| E | GLY260 |
| E | VAL285 |
| E | ASN286 |
| E | HIS287 |
| E | TYR334 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 8PW G 1341 |
| Chain | Residue |
| B | ARG235 |
| C | LYS272 |
| C | ASN312 |
| G | GLN141 |
| G | GLY145 |
| G | ALA146 |
| G | CYS147 |
| G | TRP148 |
| G | GLY191 |
| G | GLY192 |
| G | TYR193 |
| G | GLY260 |
| G | VAL285 |
| G | ASN286 |
| G | HIS287 |
| G | TYR334 |
| G | HOH2020 |
| G | HOH2034 |
| G | HOH2077 |
| site_id | AC7 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 8PW H 1341 |
| Chain | Residue |
| A | ILE202 |
| A | SER234 |
| D | HOH2110 |
| H | GLN141 |
| H | GLY145 |
| H | ALA146 |
| H | CYS147 |
| H | TRP148 |
| H | GLY191 |
| H | GLY192 |
| H | TYR193 |
| H | MET194 |
| H | GLY260 |
| H | VAL285 |
| H | ASN286 |
| H | HIS287 |
| H | TYR334 |
| H | HOH2047 |
| H | HOH2048 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 8PW F 1341 |
| Chain | Residue |
| D | SER234 |
| F | GLN141 |
| F | GLY145 |
| F | ALA146 |
| F | CYS147 |
| F | TRP148 |
| F | GLY191 |
| F | GLY192 |
| F | TYR193 |
| F | MET194 |
| F | GLY260 |
| F | VAL285 |
| F | ASN286 |
| F | HIS287 |
| F | TYR334 |
| F | HOH2049 |
| F | HOH2050 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGsCGACWAfSA |
| Chain | Residue | Details |
| A | GLN141-ALA152 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. VNHGVLVVGYG |
| Chain | Residue | Details |
| A | VAL285-GLY295 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvKNSWglnFGdqGYIrM |
| Chain | Residue | Details |
| A | TYR302-MET321 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS147 | |
| D | CYS147 | |
| D | HIS287 | |
| D | ASN307 | |
| E | CYS147 | |
| E | HIS287 | |
| E | ASN307 | |
| F | CYS147 | |
| F | HIS287 | |
| F | ASN307 | |
| G | CYS147 | |
| A | HIS287 | |
| G | HIS287 | |
| G | ASN307 | |
| H | CYS147 | |
| H | HIS287 | |
| H | ASN307 | |
| A | ASN307 | |
| B | CYS147 | |
| B | HIS287 | |
| B | ASN307 | |
| C | CYS147 | |
| C | HIS287 | |
| C | ASN307 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN120 | |
| B | ASN120 | |
| C | ASN120 | |
| D | ASN120 | |
| E | ASN120 | |
| F | ASN120 | |
| G | ASN120 | |
| H | ASN120 | |
