4BQA

Crystal structure of the ETS domain of human ETS2 in complex with DNA

Summary for 4BQA

• Entry DOI: 10.2210/pdb4bqa/pdb
• Descriptor: PROTEIN C-ETS-2, 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP)-3', ... (4 entities in total)
• Functional Keywords: transcription, transcriptional regulator, dna complex
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: P15036
• Total number of polymer chains: 9
• Total formula weight: 67610.61

Authors

Newman, J.A.,Cooper, C.D.O.,Krojer, T.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Gileadi, O. (deposition date: 2013-05-30, release date: 2013-06-12, Last modification date: 2023-12-20)

• Primary citation: Newman, J.A.,Cooper, C.D.O.,Aitkenhead, H.,Gileadi, O.; Structural Insights Into the Autoregulation and Cooperativity of the Human Transcription Factor Ets-2.; J.Biol.Chem., 290:8539-, 2015; PubMed: 25670864; DOI: 10.1074/JBC.M114.619270

Experimental method

X-RAY DIFFRACTION (2.5 Å)