4BPV

MOUSE CATHEPSIN S WITH COVALENT LIGAND

Summary for 4BPV

• Entry DOI: 10.2210/pdb4bpv/pdb
• Descriptor: CATHEPSIN S, (4R)-4-[(2-chloro-4-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}phenyl)sulfonyl]-N-{1-[(E)-iminomethyl]cyclopropyl}-1-{[1-(trifluoromethyl)cyclopropyl]carbonyl}-L-prolinamide (3 entities in total)
• Functional Keywords: hydrolase, cysteine protease, covalent ligand
• Biological source: MUS MUSCULUS (HOUSE MOUSE)
• Cellular location: Lysosome: O70370
• Total number of polymer chains: 6
• Total formula weight: 150994.69

Authors

Banner, D.W.,Benz, J.,Gsell, B.,Stihle, M.,Ruf, A.,Haap, W. (deposition date: 2013-05-28, release date: 2014-06-11)

• Primary citation: Haap, W.,Banner, D.W.; Cathepsin S Nitrile Inhibitors; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)