4BPV

MOUSE CATHEPSIN S WITH COVALENT LIGAND

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	CATHEPSIN S	polymer	225	24662.5	6	UniProt (O70370) Pfam (PF00112)	MUS MUSCULUS (HOUSE MOUSE)
2	G, H, I, J, K (A, B, C, D, E)	(4R)-4-[(2-chloro-4-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}phenyl)sulfonyl]-N-{1-[(E)-iminomethyl]cyclopropyl}-1-{[1-(trifluoromethyl)cyclopropyl]carbonyl}-L-prolinamide	non-polymer		604.0	5	Chemie (OFH)
3	L, M, N, O, P... (A, B, C, D, E...)	water	water		18.0	938	Chemie (HOH)

Sequence modifications

A, B, C, D, E, K: 116 - 340 (UniProt: O70370)

PDB	External Database	Details
Met 218	Thr 218	variant

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	147974.9
Non-Polymers*	Number of molecules	5
	Total formula weight	3019.8
All*	Total formula weight	150994.7

*Water molecules are not included.