4BKX

The structure of HDAC1 in complex with the dimeric ELM2-SANT domain of MTA1 from the NuRD complex

Summary for 4BKX

Entry DOI	10.2210/pdb4bkx/pdb
Descriptor	METASTASIS-ASSOCIATED PROTEIN MTA1, HISTONE DEACETYLASE 1, ZINC ION, ... (6 entities in total)
Functional Keywords	transcription, inositol phosphate signalling, elm2-sant domain, hdac, hdac1, histone deacetylase, mta1
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Isoform Short: Cytoplasm. Isoform Long: Nucleus: Q13330 Nucleus: Q13547
Total number of polymer chains	2
Total formula weight	75727.02
Authors	Millard, C.J.,Watson, P.J.,Celardo, I.,Gordiyenko, Y.,Cowley, S.M.,Robinson, C.V.,Fairall, L.,Schwabe, J.W.R. (deposition date: 2013-04-30, release date: 2013-07-03, Last modification date: 2023-12-20)
Primary citation	Millard, C.J.,Watson, P.J.,Celardo, I.,Gordiyenko, Y.,Cowley, S.M.,Robinson, C.V.,Fairall, L.,Schwabe, J.W.R. Class I Hdacs Share a Common Mechanism of Regulation by Inositol Phosphates. Mol.Cell, 51:57-, 2013 Cited by PubMed: 23791785 DOI: 10.1016/J.MOLCEL.2013.05.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation