4BII

How nature bridges the gap: Crystallographic elucidation of pyridomycin binding to InhA

Summary for 4BII

Entry DOI	10.2210/pdb4bii/pdb
Related	4BGE
Descriptor	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pyridomycin, ... (4 entities in total)
Functional Keywords	oxidoreductase, acp enoyl reductase
Biological source	MYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains	4
Total formula weight	117831.09
Authors	Read, J.A.,Gingell, H. (deposition date: 2013-04-10, release date: 2013-12-04, Last modification date: 2014-02-05)
Primary citation	Hartkoorn, R.,Pojer, F.,Read, J.A.,Gingell, H.,Neres, J.,Horlacher, O.,Altmann, K.H.,Cole, S. Pyridomycin Bridges the Nadh and Substrate Binding Pockets of the Enoyl Reductase Inha Nat.Chem.Biol., 10:96-, 2014 Cited by PubMed: 24292073 DOI: 10.1038/NCHEMBIO.1405 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation