4BGE
Crystal structure of InhA(S94A) mutant in complex with pyridomycin
Summary for 4BGE
Entry DOI | 10.2210/pdb4bge/pdb |
Related | 4BGI |
Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADH], Pyridomycin (3 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 6 |
Total formula weight | 174476.08 |
Authors | Pojer, F.,Hartkoorn, R.C.,Cole, S.T. (deposition date: 2013-03-26, release date: 2013-12-04, Last modification date: 2023-12-20) |
Primary citation | Hartkoorn, R.C.,Pojer, F.,Read, J.A.,Gingell, H.,Neres, J.,Horlacher, O.P.,Altmann, K.H.,Cole, S.T. Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA. Nat. Chem. Biol., 10:96-98, 2014 Cited by PubMed: 24292073DOI: 10.1038/nchembio.1405 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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