4BF2

Crystal Structures of Ask1-inhibitor Complexes

Summary for 4BF2

Entry DOI	10.2210/pdb4bf2/pdb
Related	4BIB 4BIC 4BID 4BIE
Descriptor	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5, STAUROSPORINE, GLYCEROL, ... (5 entities in total)
Functional Keywords	transferase
Biological source	HOMO SAPIENS
Cellular location	Cytoplasm: Q99683
Total number of polymer chains	2
Total formula weight	76121.11
Authors	Singh, O.,Shillings, A.,Craggs, P.,Wall, I.,Rowland, P.,Skarzynski, T.,Hobbs, C.I.,Hardwick, P.,Tanner, R.,Blunt, M.,Witty, D.R.,Smith, K.J. (deposition date: 2013-03-13, release date: 2013-07-03, Last modification date: 2023-12-20)
Primary citation	Singh, O.,Shillings, A.,Craggs, P.,Wall, I.,Rowland, P.,Skarzynski, T.,Hobbs, C.I.,Hardwick, P.,Tanner, R.,Blunt, M.,Witty, D.R.,Smith, K.J. Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design. Protein Sci., 22:1071-, 2013 Cited by PubMed: 23776076 DOI: 10.1002/PRO.2298 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.11 Å)

Structure validation