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4BBH

Plasmodium vivax N-myristoyltransferase with a bound benzothiophene inhibitor

Summary for 4BBH
Entry DOI10.2210/pdb4bbh/pdb
Related4A95 4B10 4B11 4B12 4B13 4B14
DescriptorGLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, DIMETHYL SULFOXIDE, 2-oxopentadecyl-CoA, ... (8 entities in total)
Functional Keywordstransferase, myristoylation, malaria, inhibitor
Biological sourcePLASMODIUM VIVAX
Total number of polymer chains3
Total formula weight139517.15
Authors
Rackham, M.D.,Brannigan, J.A.,Moss, D.K.,Yu, Z.,Wilkinson, A.J.,Holder, A.A.,Tate, E.W.,Leatherbarrow, R.J. (deposition date: 2012-09-23, release date: 2012-12-05, Last modification date: 2013-01-23)
Primary citationRackham, M.D.,Brannigan, J.A.,Moss, D.K.,Yu, Z.,Wilkinson, A.J.,Holder, A.A.,Tate, E.W.,Leatherbarrow, R.J.
Discovery of Novel and Ligand-Efficient Inhibitors of Plasmodium Falciparum and Plasmodium Vivax N-Myristoyltransferase.
J.Med.Chem., 56:371-, 2013
Cited by
PubMed: 23170970
DOI: 10.1021/JM301474T
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.63 Å)
Structure validation

217705

數據於2024-03-27公開中

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