4B7S

PikC D50N mutant bound to the 10-DML analog with the 3-(N,N- dimethylamino)propanoate anchoring group

Summary for 4B7S

Entry DOI	10.2210/pdb4b7s/pdb
Related	2BVJ 2C6H 2C7X 2CA0 2CD8 2VZ7 2VZM 2WHW 2WI9 3ZK5 4B7D
Descriptor	CYTOCHROME P450 HYDROXYLASE PIKC, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... (6 entities in total)
Functional Keywords	oxidoreductase, monooxygenase, pikromycin biosynthesis, inhibitor
Biological source	STREPTOMYCES VENEZUELAE
Total number of polymer chains	2
Total formula weight	99972.72
Authors	Podust, L.M. (deposition date: 2012-08-21, release date: 2013-08-28, Last modification date: 2023-12-20)
Primary citation	Negretti, S.,Narayan, A.R.H.,Chiou, K.C.,Kells, P.M.,Stachowski, J.L.,Hansen, D.A.,Podust, L.M.,Montgomery, J.,Sherman, D.H. Directing Group-Controlled Regioselectivity in an Enzymatic C-H Bond Oxygenation. J.Am.Chem.Soc., 136:4901-, 2014 Cited by PubMed: 24627965 DOI: 10.1021/JA5016052 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.84 Å)

Structure validation