4B5X

Crystal structures of divalent metal dependent pyruvate aldolase (HpaI), mutant D42A

Summary for 4B5X

Entry DOI	10.2210/pdb4b5x/pdb
Related	2V5J 2V5K 4B5S 4B5T 4B5U 4B5V 4B5W
Descriptor	4-HYDROXY-2-OXO-HEPTANE-1,7-DIOATE ALDOLASE, PHOSPHATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	lyase, catalytic mechanism
Biological source	ESCHERICHIA COLI ATCC 8739
Total number of polymer chains	2
Total formula weight	57050.03
Authors	Coincon, M.,Wang, W.,Seah, S.Y.K.,Sygusch, J. (deposition date: 2012-08-07, release date: 2012-08-29, Last modification date: 2023-12-20)
Primary citation	Coincon, M.,Wang, W.,Sygusch, J.,Seah, S.Y.K. Crystal Structure of Reaction Intermediates in Pyruvate Class II Aldolase: Substrate Cleavage, Enolate Stabilization and Substrate Specificity J.Biol.Chem., 287:36208-, 2012 Cited by PubMed: 22908224 DOI: 10.1074/JBC.M112.400705 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation