4B10
Plasmodium vivax N-myristoyltransferase with a non-hydrolysable co- factor
Summary for 4B10
Entry DOI | 10.2210/pdb4b10/pdb |
Related | 4A95 4B11 4B12 4B13 4B14 |
Descriptor | GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, 2-oxopentadecyl-CoA, DIMETHYL SULFOXIDE, ... (7 entities in total) |
Functional Keywords | transferase, malaria, drug design |
Biological source | PLASMODIUM VIVAX |
Total number of polymer chains | 3 |
Total formula weight | 138718.27 |
Authors | Yu, Z.,Brannigan, J.A.,Moss, D.K.,Brzozowski, A.M.,Wilkinson, A.J.,Holder, A.A.,Tate, E.W.,Leatherbarrow, R.J. (deposition date: 2012-07-06, release date: 2012-10-17, Last modification date: 2023-12-20) |
Primary citation | Yu, Z.,Brannigan, J.A.,Moss, D.K.,Brzozowski, A.M.,Wilkinson, A.J.,Holder, A.A.,Tate, E.W.,Leatherbarrow, R.J. Design and Synthesis of Inhibitors of Plasmodium Falciparum N-Myristoyltransferase, a Promising Target for Anti-Malarial Drug Discovery. J.Med.Chem., 55:8879-, 2012 Cited by PubMed: 23035716DOI: 10.1021/JM301160H PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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