4AZ1

Crystal structure of the Trypanosoma cruzi protein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas' disease

Summary for 4AZ1

Entry DOI	10.2210/pdb4az1/pdb
Descriptor	TYROSINE SPECIFIC PROTEIN PHOSPHATASE, 1,2-ETHANEDIOL, FORMIC ACID, ... (4 entities in total)
Functional Keywords	hydrolase, drug design
Biological source	TRYPANOSOMA CRUZI
Total number of polymer chains	2
Total formula weight	67963.60
Authors	Lountos, G.T.,Tropea, J.E.,Waugh, D.S. (deposition date: 2012-06-22, release date: 2012-11-21, Last modification date: 2023-12-20)
Primary citation	Lountos, G.T.,Tropea, J.E.,Waugh, D.S. Structure of the Trypanosoma Cruzi Protein Tyrosine Phosphatase Tcptp1, a Potential Therapeutic Target for Chagas' Disease. Mol.Biochem.Parasitol., 187:1-, 2012 Cited by PubMed: 23137716 DOI: 10.1016/J.MOLBIOPARA.2012.10.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.181 Å)

Structure validation