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4AZ1

Crystal structure of the Trypanosoma cruzi protein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas' disease

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
TYROSINE SPECIFIC PROTEIN PHOSPHATASEpolymer30233835.72UniProt (Q4E4C8)
Pfam (PF00102)
TRYPANOSOMA CRUZIPROTEIN TYROSINE PHOSPHATASE TCPTP1
2C
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
3D, E, F, G, H
(A)
FORMIC ACIDnon-polymer46.05Chemie (FMT)
4I, J
(A, B)
waterwater18.0261Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight67671.4
Non-Polymers*Number of molecules6
Total formula weight292.2
All*Total formula weight67963.6
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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