4AY6
Human O-GlcNAc transferase (OGT) in complex with UDP-5SGlcNAc and substrate peptide
Summary for 4AY6
Entry DOI | 10.2210/pdb4ay6/pdb |
Related | 1W3B 2J4O 2YDS 2YIY 4AY5 |
Descriptor | UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANS FERASE 110 KDA SUBUNIT, TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1, SULFATE ION, ... (4 entities in total) |
Functional Keywords | transferase, glycosyl transferase |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Isoform 2: Mitochondrion. Isoform 3: Cytoplasm. Isoform 4: Cytoplasm: O15294 |
Total number of polymer chains | 8 |
Total formula weight | 332013.57 |
Authors | Schimpl, M.,Zheng, X.,Blair, D.E.,Schuettelkopf, A.W.,Navratilova, I.,Aristotelous, T.,Ferenbach, A.T.,Macnaughtan, M.A.,Borodkin, V.S.,van Aalten, D.M.F. (deposition date: 2012-06-18, release date: 2012-10-24, Last modification date: 2012-12-12) |
Primary citation | Schimpl, M.,Zheng, X.,Borodkin, V.S.,Blair, D.E.,Ferenbach, A.T.,Schuettelkopf, A.W.,Navratilova, I.,Aristotelous, T.,Albarbarawi, O.,Robinson, D.A.,Macnaughtan, M.A.,Van Aalten, D.M.F. O-Glcnac Transferase Invokes Nucleotide Sugar Pyrophosphate Participation in Catalysis Nat.Chem.Biol., 8:969-, 2012 Cited by PubMed: 23103942DOI: 10.1038/NCHEMBIO.1108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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