4AT5
CRYSTAL STRUCTURE OF TRKB KINASE DOMAIN IN COMPLEX WITH GW2580
Summary for 4AT5
Entry DOI | 10.2210/pdb4at5/pdb |
Related | 1HCF 1WWB 4ASZ 4AT3 4AT4 4F0I |
Descriptor | BDNF/NT-3 GROWTH FACTORS RECEPTOR, 5-{3-methoxy-4-[(4-methoxybenzyl)oxy]benzyl}pyrimidine-2,4-diamine, GLYCEROL, ... (4 entities in total) |
Functional Keywords | transferase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 34810.20 |
Authors | Bertrand, T.,Kothe, M.,Liu, J.,Dupuy, A.,Rak, A.,Berne, P.F.,Davis, S.,Gladysheva, T.,Valtre, C.,Crenne, J.Y.,Mathieu, M. (deposition date: 2012-05-03, release date: 2012-08-22, Last modification date: 2023-12-20) |
Primary citation | Bertrand, T.,Kothe, M.,Liu, J.,Dupuy, A.,Rak, A.,Berne, P.F.,Davis, S.,Gladysheva, T.,Valtre, C.,Crenne, J.Y.,Mathieu, M. The Crystal Structures of Trka and Trkb Suggest Key Regions for Achieving Selective Inhibition. J.Mol.Biol., 423:439-, 2012 Cited by PubMed: 22902478DOI: 10.1016/J.JMB.2012.08.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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