4APC
Crystal Structure of Human NIMA-related Kinase 1 (NEK1)
Summary for 4APC
Entry DOI | 10.2210/pdb4apc/pdb |
Descriptor | SERINE/THREONINE-PROTEIN KINASE NEK1, CHLORIDE ION (3 entities in total) |
Functional Keywords | transferase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 80072.30 |
Authors | Elkins, J.M.,Hanchuk, T.D.M.,Lovato, D.V.,Basei, F.L.,Meirelles, G.V.,Kobarg, J.,Szklarz, M.,Vollmar, M.,Mahajan, P.,Rellos, P.,Zhang, Y.,Krojer, T.,Pike, A.C.W.,Bountra, C.,Arrowsmith, C.,Edwards, A.,Knapp, S. (deposition date: 2012-04-02, release date: 2012-04-25, Last modification date: 2023-12-20) |
Primary citation | Melo-Hanchuk, T.D.,Slepicka, P.F.,Meirelles, G.V.,Basei, F.L.,Lovato, D.V.,Granato, D.C.,Pauletti, B.A.,Domingues, R.R.,Leme, A.F.P.,Pelegrini, A.L.,Lenz, G.,Knapp, S.,Elkins, J.M.,Kobarg, J. NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin. Sci Rep, 7:5445-5445, 2017 Cited by PubMed: 28710492DOI: 10.1038/s41598-017-05325-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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