4APC

Crystal Structure of Human NIMA-related Kinase 1 (NEK1)

Summary for 4APC

• Entry DOI: 10.2210/pdb4apc/pdb
• Descriptor: SERINE/THREONINE-PROTEIN KINASE NEK1, CHLORIDE ION (3 entities in total)
• Functional Keywords: transferase
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 80072.30

Authors

Elkins, J.M.,Hanchuk, T.D.M.,Lovato, D.V.,Basei, F.L.,Meirelles, G.V.,Kobarg, J.,Szklarz, M.,Vollmar, M.,Mahajan, P.,Rellos, P.,Zhang, Y.,Krojer, T.,Pike, A.C.W.,Bountra, C.,Arrowsmith, C.,Edwards, A.,Knapp, S. (deposition date: 2012-04-02, release date: 2012-04-25, Last modification date: 2023-12-20)

• Primary citation: Melo-Hanchuk, T.D.,Slepicka, P.F.,Meirelles, G.V.,Basei, F.L.,Lovato, D.V.,Granato, D.C.,Pauletti, B.A.,Domingues, R.R.,Leme, A.F.P.,Pelegrini, A.L.,Lenz, G.,Knapp, S.,Elkins, J.M.,Kobarg, J.; NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin.; Sci Rep, 7:5445-5445, 2017; PubMed: 28710492; DOI: 10.1038/s41598-017-05325-w

Experimental method

X-RAY DIFFRACTION (2.1 Å)