4AL8

Structure of Dengue virus DIII in complex with Fab 2H12

Summary for 4AL8

• Entry DOI: 10.2210/pdb4al8/pdb
• Related: 4ALA 4AM0
• Descriptor: ENVELOPE PROTEIN, FAB 2H12 HEAVY CHAIN, FAB 2H12 LIGHT CHAIN, ... (5 entities in total)
• Functional Keywords: immune system, antibody, neutralisation
• Biological source: DENGUE VIRUS; More
• Total number of polymer chains: 3
• Total formula weight: 58021.60

Authors

Midgley, C.M.,Flanagan, A.,Mongkolsapaya, J.,Grimes, J.M.,Screaton, G.R. (deposition date: 2012-03-02, release date: 2012-06-06)

• Primary citation: Midgley, C.M.,Flanagan, A.,Tran, H.B.,Dejnirattisai, W.,Chawansuntati, K.,Jumnainsong, A.,Wongwiwat, W.,Duangchinda, T.,Mongkolsapaya, J.,Grimes, J.M.,Screaton, G.R.; Structural Analysis of a Dengue Cross-Reactive Antibody Complexed with Envelope Domain III Reveals the Molecular Basis of Cross-Reactivity.; J.Immunol., 188:4971-, 2012; PubMed: 22491255; DOI: 10.4049/JIMMUNOL.1200227

Experimental method

X-RAY DIFFRACTION (1.66 Å)