4AHR

Parallel screening of a low molecular weight compound library: do differences in methodology affect hit identification

Summary for 4AHR

• Entry DOI: 10.2210/pdb4ahr/pdb
• Related: 4AH9 4AHS 4AHT 4AHU 4AHV
• Descriptor: INTEGRASE, SULFATE ION, ACETIC ACID, ... (6 entities in total)
• Functional Keywords: transferase, fragment screening
• Biological source: HUMAN IMMUNODEFICIENCY VIRUS (HIV)
• Total number of polymer chains: 2
• Total formula weight: 41610.56

Authors

Wielens, J.,Heady, S.J.,Rhodes, D.I.,Mulder, R.J.,Dolezal, O.,Deadman, J.J.,Newman, J.,Chalmers, D.K.,Parker, M.W.,Peat, T.S.,Scanlon, M.J. (deposition date: 2012-02-07, release date: 2012-12-19, Last modification date: 2023-12-20)

• Primary citation: Wielens, J.,Headey, S.J.,Rhodes, D.I.,Mulder, R.J.,Dolezal, O.,Deadman, J.J.,Newman, J.,Chalmers, D.K.,Parker, M.W.,Peat, T.S.,Scanlon, M.J.; Parallel Screening of Low Molecular Weight Fragment Libraries: Do Differences in Methodology Affect Hit Identification?; J.Biomol.Screen, 18:147-, 2013; PubMed: 23139382; DOI: 10.1177/1087057112465979

Experimental method

X-RAY DIFFRACTION (1.9 Å)