4AH9
Parallel screening of a low molecular weight compound library: do differences in methodology affect hit identification
Summary for 4AH9
Entry DOI | 10.2210/pdb4ah9/pdb |
Related | 4AHR 4AHS 4AHT 4AHU 4AHV |
Descriptor | INTEGRASE, 1-(3-PHENYL-1,2,4-THIADIAZOL-5-YL)-1,4-DIAZEPANE, SULFATE ION, ... (8 entities in total) |
Functional Keywords | transferase, fragment screening |
Biological source | HUMAN IMMUNODEFICIENCY VIRUS (HIV) |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497 |
Total number of polymer chains | 2 |
Total formula weight | 42781.73 |
Authors | Wielens, J.,Heady, S.J.,Rhodes, D.I.,Mulder, R.J.,Dolezal, O.,Deadman, J.J.,Newman, J.,Chalmers, D.K.,Parker, M.W.,Peat, T.S.,Scanlon, M.J. (deposition date: 2012-02-06, release date: 2012-12-19, Last modification date: 2023-12-20) |
Primary citation | Wielens, J.,Headey, S.J.,Rhodes, D.I.,Mulder, R.J.,Dolezal, O.,Deadman, J.J.,Newman, J.,Chalmers, D.K.,Parker, M.W.,Peat, T.S.,Scanlon, M.J. Parallel Screening of Low Molecular Weight Fragment Libraries: Do Differences in Methodology Affect Hit Identification? J.Biomol.Screen, 18:147-, 2013 Cited by PubMed: 23139382DOI: 10.1177/1087057112465979 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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