4AG4

Crystal structure of a DDR1-Fab complex

Summary for 4AG4

Entry DOI	10.2210/pdb4ag4/pdb
Descriptor	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1, MONOCLONAL ANTIBODY 3E3 HEAVY CHAIN, MONOCLONAL ANTIBODY 3E3 LIGHT CHAIN, ... (6 entities in total)
Functional Keywords	immune system-transferase complex, immune system/transferase
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	3
Total formula weight	86719.74
Authors	Carafoli, F.,Mayer, M.C.,Shiraishi, K.,Pecheva, M.A.,Chan, L.Y.,Nan, R.,Leitinger, B.,Hohenester, E. (deposition date: 2012-01-24, release date: 2012-04-18, Last modification date: 2023-12-20)
Primary citation	Carafoli, F.,Mayer, M.C.,Shiraishi, K.,Pecheva, M.A.,Chan, L.Y.,Nan, R.,Leitinger, B.,Hohenester, E. Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling. Structure, 20:688-, 2012 Cited by PubMed: 22483115 DOI: 10.1016/J.STR.2012.02.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation