4AEA

Dimeric alpha-cobratoxin X-ray structure: Localization of intermolecular disulfides and possible mode of binding to nicotinic acetylcholine receptors

Summary for 4AEA

Entry DOI	10.2210/pdb4aea/pdb
Related	1CTX 1LXG 1LXH
Descriptor	LONG NEUROTOXIN 1, GLYCINE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
Functional Keywords	toxin, three-finger toxin, nicotinic acetylcholine receptor
Biological source	NAJA KAOUTHIA (MONOCLED COBRA)
Cellular location	Secreted: P01391
Total number of polymer chains	2
Total formula weight	15877.43
Authors	Rucktooa, P.,Osipov, A.V.,Kasheverov, I.E.,Filkin, S.Y.,Starkov, V.G.,Andreeva, T.V.,Bertrand, D.,Utkin, Y.N.,Tsetlin, V.I.,Sixma, T.K. (deposition date: 2012-01-09, release date: 2012-01-25, Last modification date: 2023-12-20)
Primary citation	Osipov, A.V.,Rucktooa, P.,Kasheverov, I.E.,Filkin, S.Y.,Starkov, V.G.,Andreeva, T.V.,Sixma, T.K.,Bertrand, D.,Utkin, Y.N.,Tsetlin, V.I. Dimeric Alpha-Cobratoxin X-Ray Structure: Localization of Intermolecular Disulfides and Possible Mode of Binding to Nicotinic Acetylcholine Receptors. J.Biol.Chem., 287:6725-, 2012 Cited by PubMed: 22223648 DOI: 10.1074/JBC.M111.322313 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.94 Å)

Structure validation