4AEA
Dimeric alpha-cobratoxin X-ray structure: Localization of intermolecular disulfides and possible mode of binding to nicotinic acetylcholine receptors
Summary for 4AEA
Entry DOI | 10.2210/pdb4aea/pdb |
Related | 1CTX 1LXG 1LXH |
Descriptor | LONG NEUROTOXIN 1, GLYCINE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total) |
Functional Keywords | toxin, three-finger toxin, nicotinic acetylcholine receptor |
Biological source | NAJA KAOUTHIA (MONOCLED COBRA) |
Cellular location | Secreted: P01391 |
Total number of polymer chains | 2 |
Total formula weight | 15877.43 |
Authors | Rucktooa, P.,Osipov, A.V.,Kasheverov, I.E.,Filkin, S.Y.,Starkov, V.G.,Andreeva, T.V.,Bertrand, D.,Utkin, Y.N.,Tsetlin, V.I.,Sixma, T.K. (deposition date: 2012-01-09, release date: 2012-01-25, Last modification date: 2023-12-20) |
Primary citation | Osipov, A.V.,Rucktooa, P.,Kasheverov, I.E.,Filkin, S.Y.,Starkov, V.G.,Andreeva, T.V.,Sixma, T.K.,Bertrand, D.,Utkin, Y.N.,Tsetlin, V.I. Dimeric Alpha-Cobratoxin X-Ray Structure: Localization of Intermolecular Disulfides and Possible Mode of Binding to Nicotinic Acetylcholine Receptors. J.Biol.Chem., 287:6725-, 2012 Cited by PubMed: 22223648DOI: 10.1074/JBC.M111.322313 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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