4AD4

Structure of the GH99 endo-alpha-mannosidase from Bacteroides xylanisolvens in complex with glucose-1,3-isofagomine and alpha-1,2- mannobiose

4AD4 の概要

• エントリーDOI: 10.2210/pdb4ad4/pdb
• 関連するPDBエントリー: 4ACY 4ACZ 4AD0 4AD1 4AD2 4AD3 4AD5
• 関連するBIRD辞書のPRD_ID: PRD_900111
• 分子名称: GLYCOSYL HYDROLASE FAMILY 71, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, alpha-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: hydrolase, endomannosidase, glycoside hydrolase, gh99, cazy, enzyme-carbohydrate interaction, mannose glycosidase inhibition
• 由来する生物種: BACTEROIDES XYLANISOLVENS
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44148.89

構造登録者

Thompson, A.J.,Williams, R.J.,Hakki, Z.,Alonzi, D.S.,Wennekes, T.,Gloster, T.M.,Songsrirote, K.,Thomas-Oates, J.E.,Wrodnigg, T.M.,Spreitz, J.,Stuetz, A.E.,Butters, T.D.,Williams, S.J.,Davies, G.J. (登録日: 2011-12-21, 公開日: 2012-02-01, 最終更新日: 2020-07-29)

• 主引用文献: Thompson, A.J.,Williams, R.J.,Hakki, Z.,Alonzi, D.S.,Wennekes, T.,Gloster, T.M.,Songsrirote, K.,Thomas-Oates, J.E.,Wrodnigg, T.M.,Spreitz, J.,Stutz, A.E.,Butters, T.D.,Williams, S.J.,Davies, G.J.; Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.; Proc.Natl.Acad.Sci.USA, 109:781-, 2012; PubMed: 22219371; DOI: 10.1073/PNAS.1111482109

実験手法

X-RAY DIFFRACTION (1.9 Å)