4AD5

Structure of the GH99 endo-alpha-mannosidase from Bacteroides xylanisolvens in complex with glucose-1,3-deoxymannojirimycin and alpha-1,2-mannobiose

Summary for 4AD5

Entry DOI	10.2210/pdb4ad5/pdb
Related	4ACY 4ACZ 4AD0 4AD1 4AD2 4AD3 4AD4
Related PRD ID	PRD_900111
Descriptor	GLYCOSYL HYDROLASE FAMILY 71, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, alpha-D-glucopyranose, ... (5 entities in total)
Functional Keywords	hydrolase, endomannosidase, glycoside hydrolase, gh99, cazy, enzyme-carbohydrate interaction, mannose glycosidase inhibition
Biological source	BACTEROIDES XYLANISOLVENS
Total number of polymer chains	1
Total formula weight	44164.89
Authors	Thompson, A.J.,Williams, R.J.,Hakki, Z.,Alonzi, D.S.,Wennekes, T.,Gloster, T.M.,Songsrirote, K.,Thomas-Oates, J.E.,Wrodnigg, T.M.,Spreitz, J.,Stuetz, A.E.,Butters, T.D.,Williams, S.J.,Davies, G.J. (deposition date: 2011-12-21, release date: 2012-02-01, Last modification date: 2020-07-29)
Primary citation	Thompson, A.J.,Williams, R.J.,Hakki, Z.,Alonzi, D.S.,Wennekes, T.,Gloster, T.M.,Songsrirote, K.,Thomas-Oates, J.E.,Wrodnigg, T.M.,Spreitz, J.,Stutz, A.E.,Butters, T.D.,Williams, S.J.,Davies, G.J. Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase. Proc.Natl.Acad.Sci.USA, 109:781-, 2012 Cited by PubMed: 22219371 DOI: 10.1073/PNAS.1111482109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation