4AD0
Structure of the GH99 endo-alpha-mannosidase from Bacteriodes thetaiotaomicron in complex with BIS-TRIS-Propane
Summary for 4AD0
Entry DOI | 10.2210/pdb4ad0/pdb |
Related | 4ACY 4ACZ 4AD1 4AD2 4AD3 4AD4 4AD5 |
Descriptor | ENDO-ALPHA-MANNOSIDASE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... (4 entities in total) |
Functional Keywords | hydrolase, endomannosidase, glycoside hydrolase gh99, cazy, enzyme-carbohydrate interaction, mannose glycosidase inhibition |
Biological source | BACTEROIDES THETAIOTAOMICRON |
Total number of polymer chains | 4 |
Total formula weight | 174551.42 |
Authors | Thompson, A.J.,Williams, R.J.,Hakki, Z.,Alonzi, D.S.,Wennekes, T.,Gloster, T.M.,Songsrirote, K.,Thomas-Oates, J.E.,Wrodnigg, T.M.,Spreitz, J.,Stuetz, A.E.,Butters, T.D.,Williams, S.J.,Davies, G.J. (deposition date: 2011-12-21, release date: 2012-02-01, Last modification date: 2023-12-20) |
Primary citation | Thompson, A.J.,Williams, R.J.,Hakki, Z.,Alonzi, D.S.,Wennekes, T.,Gloster, T.M.,Songsrirote, K.,Thomas-Oates, J.E.,Wrodnigg, T.M.,Spreitz, J.,Stutz, A.E.,Butters, T.D.,Williams, S.J.,Davies, G.J. Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase. Proc.Natl.Acad.Sci.USA, 109:781-, 2012 Cited by PubMed: 22219371DOI: 10.1073/PNAS.1111482109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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