4AD0
Structure of the GH99 endo-alpha-mannosidase from Bacteriodes thetaiotaomicron in complex with BIS-TRIS-Propane
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004559 | molecular_function | alpha-mannosidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004559 | molecular_function | alpha-mannosidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0004559 | molecular_function | alpha-mannosidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0004559 | molecular_function | alpha-mannosidase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE B3P A 500 |
| Chain | Residue |
| A | TYR47 |
| A | ASP287 |
| A | ARG291 |
| A | ASN294 |
| A | GLU329 |
| A | GLU332 |
| A | GOL1378 |
| A | TRP125 |
| A | HIS152 |
| A | GLU154 |
| A | TYR193 |
| A | TYR248 |
| A | PHE249 |
| A | PHE254 |
| A | TYR285 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE B3P B 500 |
| Chain | Residue |
| B | TYR47 |
| B | TRP49 |
| B | TRP125 |
| B | GLU154 |
| B | TYR193 |
| B | PHE249 |
| B | PHE254 |
| B | TYR285 |
| B | ASN294 |
| B | GLU329 |
| B | GLU332 |
| B | GOL1379 |
| B | HOH2026 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE B3P C 500 |
| Chain | Residue |
| C | TYR47 |
| C | TRP49 |
| C | TRP125 |
| C | GLU154 |
| C | TYR193 |
| C | TYR248 |
| C | PHE249 |
| C | PHE254 |
| C | TYR285 |
| C | ARG291 |
| C | GLU329 |
| C | GLU332 |
| C | GOL1379 |
| C | HOH2046 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE B3P D 500 |
| Chain | Residue |
| D | TYR47 |
| D | TRP125 |
| D | HIS152 |
| D | GLU154 |
| D | TYR193 |
| D | TYR248 |
| D | PHE249 |
| D | PHE254 |
| D | TYR285 |
| D | ARG291 |
| D | ASN294 |
| D | GLU329 |
| D | GLU332 |
| D | GOL1378 |
| D | HOH2033 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1379 |
| Chain | Residue |
| B | TYR193 |
| B | ASP194 |
| B | TYR196 |
| B | PHE249 |
| B | PHE254 |
| B | B3P500 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1378 |
| Chain | Residue |
| A | TYR193 |
| A | ASP194 |
| A | TYR196 |
| A | PHE249 |
| A | PHE254 |
| A | B3P500 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 1379 |
| Chain | Residue |
| C | TYR193 |
| C | ASP194 |
| C | TYR196 |
| C | PHE249 |
| C | PHE254 |
| C | B3P500 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 1378 |
| Chain | Residue |
| D | TYR193 |
| D | ASP194 |
| D | TYR196 |
| D | PHE249 |
| D | PHE254 |
| D | B3P500 |
