4ACY

Selenomethionine derivative of the GH99 endo-alpha-mannosidase from Bacteroides thetaiotaomicron

Summary for 4ACY

• Entry DOI: 10.2210/pdb4acy/pdb
• Related: 4ACZ 4AD0 4AD1 4AD2 4AD3 4AD4 4AD5
• Descriptor: ENDO-ALPHA-MANNOSIDASE, GLYCEROL, FORMIC ACID, ... (4 entities in total)
• Functional Keywords: hydrolase, endomannosidase, glycoside hydrolase, cazy, enzyme-carbohydrate interaction, mannose, glycosidase inhibition
• Biological source: BACTEROIDES THETAIOTAOMICRON
• Total number of polymer chains: 2
• Total formula weight: 88013.87

Authors

Thompson, A.J.,Williams, R.J.,Hakki, Z.,Alonzi, D.S.,Wennekes, T.,Gloster, T.M.,Songsrirote, K.,Thomas-Oates, J.E.,Wrodnigg, T.M.,Spreitz, J.,Stuetz, A.E.,Butters, T.D.,Williams, S.J.,Davies, G.J. (deposition date: 2011-12-21, release date: 2012-02-01, Last modification date: 2017-06-28)

• Primary citation: Thompson, A.J.,Williams, R.J.,Hakki, Z.,Alonzi, D.S.,Wennekes, T.,Gloster, T.M.,Songsrirote, K.,Thomas-Oates, J.E.,Wrodnigg, T.M.,Spreitz, J.,Stutz, A.E.,Butters, T.D.,Williams, S.J.,Davies, G.J.; Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.; Proc.Natl.Acad.Sci.USA, 109:781-, 2012; PubMed: 22219371; DOI: 10.1073/PNAS.1111482109

Experimental method

X-RAY DIFFRACTION (1.69 Å)