4A36

Structure of duck RIG-I helicase domain bound to 19-mer dsRNA and ATP transition state analogue

Summary for 4A36

• Entry DOI: 10.2210/pdb4a36/pdb
• Related: 4A2P 4A2Q 4A2V 4A2W 4A2X
• Descriptor: RETINOIC ACID INDUCIBLE PROTEIN I, 5'-R(*GP*CP*AP*UP*GP*CP*GP*AP*CP*CP*UP*CP*UP*GP *UP*UP*UP*GP*A)-3', 5'-R(*UP*CP*AP*AP*AP*CP*AP*GP*AP*GP*GP*UP*CP*GP *CP*AP*UP*GP*C)-3', ... (6 entities in total)
• Functional Keywords: rna binding protein-rna complex, superfamily 2 rna helicase, atp and dsrna binding, antiviral signalling pathway, rna binding protein/rna
• Biological source: ANAS PLATYRHYNCHOS; More
• Total number of polymer chains: 6
• Total formula weight: 151994.56

Authors

Kowalinski, E.,Lunardi, T.,McCarthy, A.A.,Cusack, S. (deposition date: 2011-09-30, release date: 2011-10-19, Last modification date: 2023-12-20)

• Primary citation: Kowalinski, E.,Lunardi, T.,Mccarthy, A.A.,Louber, J.,Brunel, J.,Grigorov, B.,Gerlier, D.,Cusack, S.; Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA.; Cell(Cambridge,Mass.), 147:423-, 2011; PubMed: 22000019; DOI: 10.1016/J.CELL.2011.09.039

Experimental method

X-RAY DIFFRACTION (3.7 Å)