4A36

Structure of duck RIG-I helicase domain bound to 19-mer dsRNA and ATP transition state analogue

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	RETINOIC ACID INDUCIBLE PROTEIN I	polymer	556	63329.5	2	UniProt (D3TI84) Pfam (PF00270) Pfam (PF18119) Pfam (PF00271) In PDB	ANAS PLATYRHYNCHOS	RIG-I
2	R, T	5'-R(*GP*CP*AP*UP*GP*CP*GP*AP*CP*CP*UP*CP*UP*GP *UP*UP*UP*GP*A)-3'	polymer	19	6031.6	2		SYNTHETIC CONSTRUCT	19-MER
3	S, U	5'-R(*UP*CP*AP*AP*AP*CP*AP*GP*AP*GP*GP*UP*CP*GP *CP*AP*UP*GP*C)-3'	polymer	19	6100.7	2		SYNTHETIC CONSTRUCT	19-MER
4	A, B	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
5	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6	A, B	ALUMINUM FLUORIDE	non-polymer		84.0	2	Chemie (AF3)

Sequence modifications

A, B: 242 - 794 (UniProt: D3TI84)

PDB	External Database	Details
Gly 239	-	expression tag
Ala 240	-	expression tag
Met 241	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	150923.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1071.0
All*	Total formula weight	151994.6

*Water molecules are not included.