4A2X

Structure of duck RIG-I C-terminal domain (CTD) with 14-mer dSRNA

Summary for 4A2X

• Entry DOI: 10.2210/pdb4a2x/pdb
• Related: 4A2P 4A2Q 4A2V 4A2W 4A36
• Descriptor: RETINOIC ACID INDUCIBLE PROTEIN I, 5'-R(*GP*GP*GP*AP*GP*AP*AP*CP*AP*AP*CP*GP*CP*GP)-3', 5'-R(*CP*GP*CP*GP*UP*UP*GP*UP*UP*CP*UP*CP*CP*CP)-3', ... (4 entities in total)
• Functional Keywords: rna binding protein-rna complex, superfamily 2 rna helicase, atp and dsrna binding, antiviral signalling pathway, rna binding protein/rna
• Biological source: ANAS PLATYRHYNCHOS (MALLARD DUCK); More
• Total number of polymer chains: 8
• Total formula weight: 78868.67

Authors

Kowalinski, E.,Lunardi, T.,McCarthy, A.A.,Cusack, S. (deposition date: 2011-09-29, release date: 2011-10-19, Last modification date: 2023-12-20)

• Primary citation: Kowalinski, E.,Lunardi, T.,McCarthy, A.A.,Louber, J.,Brunel, J.,Grigorov, B.,Gerlier, D.,Cusack, S.; Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA.; Cell, 147:423-435, 2011; PubMed: 22000019; DOI: 10.1016/j.cell.2011.09.039

Experimental method

X-RAY DIFFRACTION (4 Å)