4A26
The crystal structure of Leishmania major N5,N10- methylenetetrahydrofolate dehydrogenase/cyclohydrolase
Summary for 4A26
Entry DOI | 10.2210/pdb4a26/pdb |
Descriptor | PUTATIVE C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC, CHLORIDE ION (3 entities in total) |
Functional Keywords | oxidoreductase, hydrolase, leishmaniasis |
Biological source | LEISHMANIA MAJOR |
Total number of polymer chains | 2 |
Total formula weight | 64023.77 |
Authors | Eadsforth, T.C.,Cameron, S.,Hunter, W.N. (deposition date: 2011-09-22, release date: 2011-10-26, Last modification date: 2023-12-20) |
Primary citation | Eadsforth, T.C.,Cameron, S.,Hunter, W.N. The Crystal Structure of Leishmania Major N(5),N(10)-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase and Assessment of a Potential Drug Target. Mol.Biochem.Parasitol., 181:178-, 2012 Cited by PubMed: 22108435DOI: 10.1016/J.MOLBIOPARA.2011.11.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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