4A03
Crystal Structure of Mycobacterium tuberculosis DXR in complex with the antibiotic FR900098 and cofactor NADPH
Summary for 4A03
| Entry DOI | 10.2210/pdb4a03/pdb |
| Related | 2C82 2JCV 2JCX 2JCY 2JCZ 2JD0 2JD1 2JD2 2Y1C 2Y1D 2Y1E 2Y1F 2Y1G |
| Descriptor | 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, MANGANESE (II) ION, 3-[ethanoyl(hydroxy)amino]propylphosphonic acid, ... (6 entities in total) |
| Functional Keywords | oxidoreductase, fr900098, mep pathway |
| Biological source | MYCOBACTERIUM TUBERCULOSIS |
| Total number of polymer chains | 2 |
| Total formula weight | 85489.01 |
| Authors | Bjorkelid, C.,Bergfors, T.,Jones, T.A. (deposition date: 2011-09-07, release date: 2012-01-18, Last modification date: 2023-12-20) |
| Primary citation | Bjorkelid, C.,Bergfors, T.,Unge, T.,Mowbray, S.L.,Jones, T.A. Structural Studies on Mycobacterium Tuberculosis Dxr in Complex with the Antibiotic Fr-900098. Acta Crystallogr.,Sect.D, 68:134-, 2012 Cited by PubMed: 22281742DOI: 10.1107/S0907444911052231 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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