4YJ3
Crystal structure of tubulin bound to compound 2
Summary for 4YJ3
Entry DOI | 10.2210/pdb4yj3/pdb |
Related | 4YJ2 |
Descriptor | Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, IMIDAZOLE, ... (12 entities in total) |
Functional Keywords | alpha-tubulin, beta-tubulin, stathmin, mi-181, cell cycle inhibitor complex, microtubule, cytoskeleton, cell cycle |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 6 |
Total formula weight | 264817.77 |
Authors | McNamara, D.E.,Torres, J.Z.,Yeates, T.O. (deposition date: 2015-03-03, release date: 2015-05-27, Last modification date: 2023-09-27) |
Primary citation | McNamara, D.E.,Senese, S.,Yeates, T.O.,Torres, J.Z. Structures of potent anticancer compounds bound to tubulin. Protein Sci., 24:1164-1172, 2015 Cited by PubMed: 25970265DOI: 10.1002/pro.2704 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.75 Å) |
Structure validation
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