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4YJ2

Crystal structure of tubulin bound to MI-181

Summary for 4YJ2
Entry DOI10.2210/pdb4yj2/pdb
Related4YJ3
DescriptorTubulin alpha-1B chain, 5,6-dimethyl-2-[(E)-2-(pyridin-3-yl)ethenyl]-1,3-benzothiazole, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (13 entities in total)
Functional Keywordsalpha-tubulin, beta-tubulin, stathmin, mi-181, cell cycle inhibitor complex, microtubule, cytoskeleton, cell cycle
Biological sourceRattus norvegicus (Rat)
More
Total number of polymer chains6
Total formula weight265273.32
Authors
McNamara, D.E.,Torres, J.Z.,Yeates, T.O. (deposition date: 2015-03-03, release date: 2015-05-27, Last modification date: 2023-09-27)
Primary citationMcNamara, D.E.,Senese, S.,Yeates, T.O.,Torres, J.Z.
Structures of potent anticancer compounds bound to tubulin.
Protein Sci., 24:1164-1172, 2015
Cited by
PubMed: 25970265
DOI: 10.1002/pro.2704
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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