4XG2
Crystal structure of ligand-free Syk
Summary for 4XG2
Entry DOI | 10.2210/pdb4xg2/pdb |
Related | 4XG3 4XG4 4XG5 4XG6 4XG7 4XG8 4XG9 |
Descriptor | Tyrosine-protein kinase SYK (2 entities in total) |
Functional Keywords | syk kinase, inhibitor, spleen tyrosine kinase, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane : P43405 |
Total number of polymer chains | 1 |
Total formula weight | 33900.96 |
Authors | |
Primary citation | Lee, S.J.,Choi, J.S.,Han, B.G.,Kim, H.S.,Song, H.J.,Lee, J.,Nam, S.,Goh, S.H.,Kim, J.H.,Koh, J.S.,Lee, B.I. Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs Febs J., 283:3613-3625, 2016 Cited by PubMed: 27504936DOI: 10.1111/febs.13831 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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