4XFH

cysteine dioxygenase variant - Y157F at pH 6.2 with cysteine

Summary for 4XFH

Entry DOI	10.2210/pdb4xfh/pdb
Related	4EXT 4IEO 4IEP 4IEQ 4IER 4IES 4IET 4IEU 4IEV 4IEW 4IEX 4IEY 4IEZ 4JTN 4JTO 4KWK 4KWL 4PIX 4PIY 4PIZ 4PJY 4XEZ 4XF0 4XF1 4XF3 4XF4 4XF9 4XFA 4XFB 4XFC 4XFF 4XFG 4XFI
Descriptor	Cysteine dioxygenase type 1, FE (III) ION, CYSTEINE, ... (4 entities in total)
Functional Keywords	cupin fold, cysteine to cysteine sulfinic acid catalysis, thiol dioxygenase, oxidoreductase
Biological source	Rattus norvegicus (Rat)
Total number of polymer chains	1
Total formula weight	23219.89
Authors	Driggers, C.M.,Karplus, P.A. (deposition date: 2014-12-26, release date: 2016-02-24, Last modification date: 2023-09-27)
Primary citation	Driggers, C.M.,Kean, K.M.,Hirschberger, L.L.,Cooley, R.B.,Stipanuk, M.H.,Karplus, P.A. Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428:3999-4012, 2016 Cited by PubMed: 27477048 DOI: 10.1016/j.jmb.2016.07.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation