4IET

Cys-persulfenate bound Cysteine Dioxygenase at pH 6.8 in the presence of Cys

Summary for 4IET

Entry DOI	10.2210/pdb4iet/pdb
Related	4IEO 4IEP 4IEQ 4IER 4IES 4IEU 4IEV 4IEW 4IEX 4IEY 4IEZ 4IF0 4IF1
Descriptor	Cysteine dioxygenase type 1, FE (II) ION, S-HYDROPEROXYCYSTEINE, ... (4 entities in total)
Functional Keywords	cupin fold, catalyzes oxidation, cysteine to cysteine sulfinate, c93-y157 crosslink, cytosol, oxidoreductase
Biological source	Rattus norvegicus (brown rat,rat,rats)
Total number of polymer chains	1
Total formula weight	23267.89
Authors	Driggers, C.M.,Cooley, R.B.,Karplus, P.A. (deposition date: 2012-12-13, release date: 2013-06-26, Last modification date: 2015-06-24)
Primary citation	Driggers, C.M.,Cooley, R.B.,Sankaran, B.,Hirschberger, L.L.,Stipanuk, M.H.,Karplus, P.A. Cysteine dioxygenase structures from pH4 to 9: consistent cys-persulfenate formation at intermediate pH and a Cys-bound enzyme at higher pH. J.Mol.Biol., 425:3121-3136, 2013 Cited by PubMed: 23747973 DOI: 10.1016/j.jmb.2013.05.028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation