4WF4
Crystal structure of E.Coli DsbA co-crystallised in complex with compound 4
Summary for 4WF4
Entry DOI | 10.2210/pdb4wf4/pdb |
Related | 1FVK 4WET 4WEY 4WF5 |
Descriptor | Thiol:disulfide interchange protein, 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, ... (4 entities in total) |
Functional Keywords | disulfide oxidoreductase, redox protein, dsba, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Escherichia coli BL21(DE3) |
Total number of polymer chains | 2 |
Total formula weight | 42659.38 |
Authors | Adams, L.A.,Sharma, P.,Mohanty, B.,Ilyichova, O.V.,Mulcair, M.D.,Williams, M.L.,Gleeson, E.C.,Totsika, M.,Doak, B.C.,Caria, S.,Rimmer, K.,Shouldice, S.R.,Vazirani, M.,Headey, S.J.,Plumb, B.R.,Martin, J.L.,Heras, B.,Simpson, J.S.,Scanlon, M.J. (deposition date: 2014-09-12, release date: 2015-01-21, Last modification date: 2024-10-16) |
Primary citation | Adams, L.A.,Sharma, P.,Mohanty, B.,Ilyichova, O.V.,Mulcair, M.D.,Williams, M.L.,Gleeson, E.C.,Totsika, M.,Doak, B.C.,Caria, S.,Rimmer, K.,Horne, J.,Shouldice, S.R.,Vazirani, M.,Headey, S.J.,Plumb, B.R.,Martin, J.L.,Heras, B.,Simpson, J.S.,Scanlon, M.J. Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54:2179-2184, 2015 Cited by PubMed: 25556635DOI: 10.1002/anie.201410341 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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