Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4WEY

Crystal structure of E.Coli DsbA in complex with compound 17

Summary for 4WEY
Entry DOI10.2210/pdb4wey/pdb
Related1FVK 4WET 4WF4 4WF5
DescriptorThiol:disulfide interchange protein, 1,2-ETHANEDIOL, N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}carbonyl)-L-serine, ... (4 entities in total)
Functional Keywordsdisulfide oxidoreductase, redox protein, dsba, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceEscherichia coli BL21(DE3)
Total number of polymer chains2
Total formula weight42746.45
Authors
Primary citationAdams, L.A.,Sharma, P.,Mohanty, B.,Ilyichova, O.V.,Mulcair, M.D.,Williams, M.L.,Gleeson, E.C.,Totsika, M.,Doak, B.C.,Caria, S.,Rimmer, K.,Horne, J.,Shouldice, S.R.,Vazirani, M.,Headey, S.J.,Plumb, B.R.,Martin, J.L.,Heras, B.,Simpson, J.S.,Scanlon, M.J.
Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA.
Angew.Chem.Int.Ed.Engl., 54:2179-2184, 2015
Cited by
PubMed: 25556635
DOI: 10.1002/anie.201410341
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.55 Å)
Structure validation

217157

PDB entries from 2024-03-13

PDB statisticsPDBj update infoContact PDBjnumon