4U7F

Reduced quinone reductase 2 in complex with CK2 inhibitor DMAT

Summary for 4U7F

• Entry DOI: 10.2210/pdb4u7f/pdb
• Related: 4U7G 4U7H
• Descriptor: Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
• Functional Keywords: reduced quinone reductase 2, dmat, ck2 inhibitor, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: P16083
• Total number of polymer chains: 2
• Total formula weight: 54354.17

Authors

Leung, K.K.,Shilton, B.H. (deposition date: 2014-07-30, release date: 2015-02-11, Last modification date: 2023-12-27)

• Primary citation: Leung, K.K.,Shilton, B.H.; Quinone Reductase 2 Is an Adventitious Target of Protein Kinase CK2 Inhibitors TBBz (TBI) and DMAT.; Biochemistry, 54:47-59, 2015; PubMed: 25379648; DOI: 10.1021/bi500959t

Experimental method

X-RAY DIFFRACTION (1.8 Å)